Couple of tidbits from pre-order pages:
Born in the City, Hawthorne left as a teen to seek a life of freedom in the wilderness outside the safety of our walls. She has survived for years outside of Guardians protection, and has come to learn her true purpose: To provide shelter to humanity by helping them not only survive, but lead a better way of life.
Humanitys last safe city has fallen to an overwhelming invasion force, led by Ghaul, the imposing commander of the brutal Red Legion. He has stripped the citys Guardians of their power, and forced the survivors to flee. You will venture to mysterious, unexplored worlds of our solar system to discover an arsenal of weapons and devastating new combat abilities. To defeat the Red Legion and confront Ghaul, you must reunite humanitys scattered heroes, stand together, and fight back to reclaim our home."