I think the most important scene involved WHAT was whispered by the Doctor into the sheriffs ear? I don't think it was anything related to the blood work he did on everyone (may be wrong). I think it was more.......
That's not a plot hole. It's merely something not explained, which it wasn't (or hasn't been explained yet) in the comics. Plus it's not like this is a new thing, the zombie outbreak in Night of the Living Dead was never explained either.
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