I used to live down in market sq area, and my family would park in locust street garage. If you know what is best and would like to actually tailgate, go all the way to the top, it is open air, and honestly a nice area. It is 10 bucks to park, and has an easy out to I-40.
Also there is a shuttle that picks you up right in front of market sq. It is 4 bucks R/T and drops you off in front of the science building next about a 1/4 mile from stadium, and will bring you back from the same place, after the game....very convenient