I've seen some very good points in this thread.
I count two thus far, not including the guy who said "Good post" to me.
The spread is a fad, namely the spread option. As I have posted many times the spread option like Florida runs is long term suicide. Many thinking coaches figured out a long time ago if you keep running your QB you will get him killed, then your offense dies.
They said the same thing about the T formation, the wing-T (which I hate), the single back set, the shotgun, the empty backfield, the wishbone, and pretty much any new formation.
Running your quarterback has no more risk than using a conventional running back, primarily because most of the time the offense that runs the quarterback creates one-on-one matchups for the receivers. This creates a much greater margin of error than a precisely-timed passing attack does. Want to stop Hawaii? Get on the line and hammer those receivers. Want to stop Navy? You can't do the same thing because they'll destroy you.
A regular spread that just adds receivers onto the field and spreads out the defense is much better.
Only if you have the personnel to do it. Florida ran a lot of two-receiver sets this year with four guys in the backfield (basically a split single wing) and their offense was terrific.
I still like a Pro-Set like Tennessee runs. It is actually more multiple than the spread and doesn't rely on a running QB. All types of QB's can be successfull in this type of offense that features the all important powerfull running game.
Anything can be "multiple" if you have a smart guy running the offense. There is nothing that is inherently more "multiple" than the next.
Defensively, to stop the spread I think that the 4-3 is fine if you have speedy LB's that can drop into pass coverage easily. I think that using a spy on the QB can be highly benificial, particularly at the middle LB position. If you have a good DL this would be all the more effective.
Using a spy can be beneficial, but the purpose of the option is to leave certain players (reads) unblocked in order to create numerical mismatches. The word "option" can refer to any of about 30 different plays; a good option coach will find something that works and your best-drawn defensive schemes will be laid waste to.
If your LB's are not good enough in pass coverage the nickle would be a better choice IMO.
Then you're creating situations where your fastest blockers (which is what option receivers are) can tee off on guys who are unwilling to be physical. Let's be honest here; a huge part of the success of the option is that defensive backs simply don't like to be hit. Having them get clocked time and again by receivers is a nice way to scare the crap out of them.
And if that fails, I have a play that involves a tackle pulling out to get the cornerback.
