Latest Coronavirus - Yikes

#31,003
#31,003
luthervol said:
I don't think anyone blames politicians for natural occurrences, but they do rightfully access their preparedness and response.
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It all depends on which side of the aisle a person.... judging from what is going on in the world the response has been similar.... we have just have to rush to get medicines can help in some way.
 
#31,011
#31,011
The conspiracy theorist in me wonders if the response to this is an elaborate form of social engineering, conditioning us for widespread government crackdowns becoming the norm in the future.

IDK, I just have a feeling that something nefarious is going on here.
 
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#31,012
#31,012
Purple Tiger said:
How so? A lot of people who died were never been tested.
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I thought that too, but I think they are testing people that died to rule out Covid-19. Here in Georgia they initially listed an 11 year old as a victim, but when back and changed it once his test came back negative.
 
#31,014
#31,014
DC_Vol said:
Maybe. There is no doubt the number of current infections is understated. The mortality rate will ultimately be restated to lower than the current figure.
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The mortality rate as stated by who? Current mortality rate estimates are 0.5%-1% with (likely) the most accepted being 0.66%. I would not say there is “no doubt” that is lowered, though it’s possible.

If you are talking about confirmed deaths divided by confirmed cases, then that isn’t the mortality rate. That’s the Case Fatality Rate (CFR) - every epidemic has one. And it is correct by definition for any point in time.

I would agree there is no doubt that the CFR of the general population will be higher than the mortality rate. There is certainly some number of undiagnosed cases and the percentage of those is almost certainly higher than the percentage of undiagnosed (COVID-associated) deaths.
 
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#31,018
#31,018
luthervol said:
As far as the memes that I see, it's much better and far more honestly accurate than most.
Since the study focuses on vaccines, were there actions taken on the bolded recommendations?
After all, it does seem as if the development of a vaccine is the only thing that is going to end this.
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Study and development cell and recombinant technologies are ongoing and constant, and have been for some time. There is no drop-in panacea for egg-based vaccines, and why I stated there wasn't anything to heed in this Sept. report that could have changed response to a Dec. (or November) C19 outbreak.

Here's a 2018 statement excerpt:
Remarks from FDA Commissioner Scott Gottlieb, M.D., as prepared for oral testimony before the U.S. House Committee on Energy and Commerce Subcommittee on Oversight and Investigations hearing “Examining U.S. Public Health Preparedness for and Response Efforts to Seasonal Influenza.”

While we should continue to focus on the discovery of a new breakthrough vaccine, we also must consider what immediate and intermediate steps we can take to enhance the production of existing licensed vaccines. And what should be done to invest in advanced domestic manufacturing to ensure new and existing technologies are scalable so that manufacturers can meet domestic and global demand.

There have been successes in developing alternatives to egg-based vaccines, such as cell-based and recombinant technologies, in part because of the collaborations and work by BARDA. However, despite these advances in vaccine development, the majority of manufacturers are continuing to produce egg-based vaccines.

There are reasons for this. The egg-based process works. And the vaccines are safe and effective. But even more so, it would require an enormous investment to fundamentally change manufacturing.

However, we believe it’s worth better understanding the potential of cell-based and recombinant alternatives.

Some studies have found that cell-based and recombinant vaccines are more efficacious, or could be more efficacious, than egg-based vaccines; but, more data and analyses are needed.

As one step to better understand the differences between egg-based and cell-based technologies, we’re using CMS data to compare Medicare patients that received a cell-based vaccine to those who received an egg-based vaccine to determine which vaccine was more effective in that population.

As we consider greater investment in alternative vaccine development processes, it’s important to note, however, that there are also challenges with these newer cell-based approaches.

To help address these challenges, the FDA is working to help develop more effective cell lines that can be better scaled through continuous manufacturing.

We’re also looking at how we develop a more robust recombinant vaccine manufacturing process to increase yield, while reducing cost.

Continuous manufacturing holds great promise for both cell-based and recombinant vaccines, because supply could be more easily ramped up on short notice.

This would allow us to more rapidly address newly emerging strains or strain drift. Getting all the necessary preparatory work done is one of the limiting steps of egg-based technologies.

The FDA can help industry make investments in these new manufacturing technologies, and facilitate such a transition. Remarks from FDA Commissioner Scott Gottlieb, M.D., as prepared for oral testimony before the U.S. House Committee on Energy and Commerce Subcommittee on Oversight and Investigations hearing “Examining U.S. Public Health Preparedness for and Response Efforts to Seasonal Influenza.”

U.S. intel issues such pandemic warnings every year in the 'Worldwide Threat Assessment' reports, though much briefer, less detailed.

 
#31,022
#31,022
rjd970 said:
Even if true, IF True, then we are still counting anybody that dies, regardless of cause, as a COVID-19 death if they test positive.

We do know, for a fact, that underlying causes are the contributor to death and the majority of people that don’t have underlying issues aren’t dying. To just assume there are a lot more deaths to healthy people we don’t know about is dumb.

These daily death numbers are more reflective of problems with COPD, diabetes, respiratory illnesses, and other chronic conditions. There is nothing in the data, NOTHING, that suggests that if those with chronic illnesses were healthy they still would have been killed by corona.
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We do this to some extent for every virus tracked from a public health perspective. Go look at flu deaths.
 
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