I agree that 3-4 and 4-2-5 can both be effective defenses when employed correctly with the proper personell. I think your statement about blitzing probably applies more to the 3-4 (or really any base 3 defense) than the 4-2-5. The 4-2-5, like a 4-3, would ideally have the line handling rush duties without needing the blitz, while a 3-4, generally will have a lb coming as well as the line. A 4-2-5, at the heart, trades a lb for a ss. This means you have ss generally playing more run support than you would in a 4-3. Tcu plays alot of passing teams on it's schedule and the 4-2-5 is a good fit for that. A 4-2-5 gives a good base that won't require them to constantly play a nickel package.
The most effective offenses right now are either very balanced or actually prefer to run the ball. Look at auburn and Oregon. If you can't stop the run, they will run all day long. Even a pass oriented coach like spurrier shows that his offense is much more effective when he has lattimore and can run. Also look at florida when they were winning. Yes, they passed, but the offense was run driven. Look what happened when they stopped being able to run. Look at even miss st this year.
The point is that more and more good teams are run first. If tcu faced the teams teen does each year, I doubt they would stay with a 4-2-5, because all things being equal, it is not as good as a 4-3 at stopping the run. Ask almost any coach if they know a run is coming would they rather have an extra lb or a ss and I know what they will say.
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