This time of year, my main recommendation would be to stay hydrated.
I'm not kidding.
My next top ten advice:
2. If your room sucks, don't worry about it as you will not spend any time in it.
3. If you want to meet women, stay away from the older hotels and casinos, especially downtown.
4. Do not, under any circumstances, even take the handouts for the escort services. You will see a zillion people on the streets handing these things out. If you let them put even one in your hand, the rest will descend on you like locusts.
5. Don't feel like a man and decide you have to walk everywhere. If its more than a mile in this heat, take a cab.
6. Avoid gambling alongside your friends who claim to have the numbers down pat, i.e. the guy who can cut the house edge in blackjack to 2 percent. The reason is that cutting the house advantage down like that works only if you play 10,000 hands, and you aren't there to do that. Admit that you are hoping lightning strikes and take some chances.
7. Assume that you will lose everything you go with.
8. Don't take your ATM card with you.
9. Most of the liquor they give you for free is cheap. And you will feel it in the morning, for sure. If you are going to go on a binge, pay for the drinks.
10. Nothing out there is really free. Nothing.