I've got a feeling that this is how they will end the show... Rick is going to lose it a little at a time over and over again, and he's going to run off trying to catch the ghost of Lori. Somewhere along the way he will be eaten or bit by a zombie and the rest of the group will crack and either get bit or go off on there own.
It almost looked to me that Merle and Daryl might be going out fighting too. Maybe just Merle will get bit and Daryl will return to help Rick out, who knows?