Well, all defenses work better if the DL can get pressure. The Tampa D doesn't really differentiate itself on DL play (although the two DTs have different responsibilities than many other Ds). It works best with at least one speed rusher at DE, and if the front 4 can get pressure w/o outside help, the defense can just suffocate you.
The BIG difference is in the bottom 7. It relies on fast, speedy linebackers that can cover AND tackle. It also has minimal one-on-one coverage by the CBs, protecting them by keeping the safeties deep. Barber in Tampa is a good example of the kind of corner who succeeds in this defense; Barber doesn't have the pure speed to really cover fast WRs in many other defenses (and would get killed in the old Chicago 54 IMO), but when he's just responsibile for a specific area of the field, his intelligence, willingness to tackle, and ball skills make him a Pro Bowler.
A guy like Al Wilson or Kevin Burnett would be INCREDIBLE in this D. Not that they'd be terrible in another D, but if they played in the Kiffen D, I think they would've both been top 10 draft picks.