MercyPercy
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Yea I'm not a fan of stuff like this
Just some quick notes here. I'm generally a fan of Colossal's stated goals but this situation was more of a PR stunt than anything. Firstly, a lot of people don't really understand what they are actually doing and what they did here. They aren't taking actual 12,000 year old dire wolf (aenocyon dirus) DNA and "splicing" it with wolf DNA to create some jurassic park hybrid. All they did here was use CRISPR to edit like 14 genes from a standard gray wolf (canis lupus). They said they've compared the DNA sequencing from a couple aenocyon tooth and bone specimens to get the data they needed to know what genes to affect in the gray wolf to give it similar traits to aenocyon dirus. I don't think they claimed it's 100% match. It's a designer wolf. Despite probably looking very similar to gray wolves though, aenocyon was actually separated by millions of years of evolution. They aren't even the same genus. It's actually a much more difficult task compared to using a modified Asian elephant to make a woolly mammoth (they diverged more recently), which is again the same exact process they will be using.
It brings up an interesting philosophical question that may be better suited in a different thread though. Let's say we 1). Had enough dna data to know for 100% certain the exact differences in their DNA, and 2.) could perfectly modify every gene needed in a gray wolf so that its genetic sequencing is a 100% match to aenocyon. Is the new animal a dire wolf or still a designer gray wolf? Is it a difference without distinction? In a more extreme example, if we edited the genome of a chicken and it looked exactly like a veolicraptor, is it a jacked up murder chicken or did we revive an extinct species? No movie magic mosquito amber splicing needed. Not going to happen (at least any time soon) but it's a fun thought experiment.
This specific situation is blowing up in Colossal's face a little bit partly because they really played into the Game of Thrones angle (very silly) and don't do a great job of explaining what they are actually doing, but people also don't read and make assumptions about what it means in reality to jurassic park a species under the limits of current technology and they let their imaginations run wild.
As far as I know I don't think they have much of any reason to actually bring back dire Wolves to reintroduce them. They were likely outcompeted by gray wolves and there's no reason to think they still wouldn't be. Anywhere they would be helpful to reintroduce in the wild could be done with gray wolves. The woolly mammoth is entirely different.
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