CTE in young donors
CTE is an Alzheimer’s-like disease has been most commonly associated with former professional football players, but has also been detected in military veterans, including many who have been exposed to roadside bombs and other types of military blasts.
Previous studies have shown that repetitive hits to the head — even without concussion — can result in CTE.
Most of the donors analyzed in this recent study played football (60%), followed by soccer (15%) and ice hockey (10%). Other sports included in the study that resulted in CTE diagnosis are amateur wrestling, rugby and professional wrestling.
The donors’ ages at the time of death ranged from 13 to 29 years old. The youngest person diagnosed with CTE in the study was a 17-year-old high school football player, McKee told CNN.
Brain donors who died before they reached 30 were selected to minimize any contribution from age-related conditions, the study authors said.
https://www.cnn.com/2023/07/16/health/race-to-reform-alzheimers-disease-diagnosis
https://www.cnn.com/2023/07/16/health/race-to-reform-alzheimers-disease-diagnosis
With new therapies that promise to slow Alzheimer’s disease, researchers race to reform how patients are diagnosed
Because a majority of the CTE samples previously evaluated came from older adults, looking at younger brains can provide an important perspective, said Dr. Julie Stamm, a clinical assistant professor at the University of Wisconsin-Madison who was not involved with the new study.
“As people get older, there are age-related neurodegenerative changes, and just general degenerative changes that are happening,” Stamm said. “So, looking at the younger brains gives the ability to look at the CTE pathology without all of these other comorbid pathologies.”
Another important facet of the study is that amateur athletes comprised 71.4% of those diagnosed with CTE.
Of the 48 donors diagnosed with CTE who played football, 37 were amateur football players and 11 played for the NFL. Position played made no difference in developing CTE, but those who played longer were more likely to be diagnosed with the disease. On average, those that had CTE played football for 2.8 years longer than those that didn’t develop the disease.