Coronavirus (No politics)

Looks like Pfizer has good results with their oral antiviral. 0 out of 389 who had covid died who got the drug vs 7 out of 385 who got placebo. Trial stopped early as the safety monitors thought it would be unethical to continue placebo. Hopefully they will publish their results soon.


So now that they have what seems to be an effective treatment (long term safety tbd) what is the rationale for vaccination or boosters?
 
So now that they have what seems to be an effective treatment (long term safety tbd) what is the rationale for vaccination or boosters?
Good question. Think vaccines still are helpful as there are going to be limitations on who would benefit and could take this drug.

Assuming this drug works as reported it was only given very early in treatment (within 5 days of symptoms starting) and only to high risk individuals. Likely if given after 5-7 days of symptoms then the drug won’t work as the virus stops replicating. A lot of people with covid don’t present to the doctor until the 2nd week.

This drug also will interact with a lot of commonly used medications such as many blood pressure meds, anticoagulants, and other heart related meds to name a few making it not an option for many people.
With vaccine you don’t really have to worry about any of those things and even with delta decreasing overall effectiveness the vaccines still doing a good job decreasing hospitalization and death. Hopefully they publish their results soon from the trial.
 
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Colorado spiking through the roof.

Crazy because I’ve been out there during the pandemic, they aren’t messing around about masks. Everyone was wearing them, even driving alone in their cars.

We stayed in Aspen for a few days and even outside walking around you had to wear them. There were signs everywhere outdoors and police would tell people to put theirs on.
 
Colorado spiking through the roof.

Crazy because I’ve been out there during the pandemic, they aren’t messing around about masks. Everyone was wearing them, even driving alone in their cars.

We stayed in Aspen for a few days and even outside walking around you had to wear them. There were signs everywhere outdoors and police would tell people to put theirs on.
Why are Colorado COVID-19 cases spiking?
Unvaccinated people are spreading it.

Those who are unvaccinated comprise about 80% of infections. At UCHealth hospitals, that ratio holds: 78% of those hospitalized and 91% of those in ICUs are unvaccinated. The ones hospitalized despite being vaccinated are often immunocompromised or significantly older.
 
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Why are Colorado COVID-19 cases spiking?
Unvaccinated people are spreading it.

Those who are unvaccinated comprise about 80% of infections. At UCHealth hospitals, that ratio holds: 78% of those hospitalized and 91% of those in ICUs are unvaccinated. The ones hospitalized despite being vaccinated are often immunocompromised or significantly older.

The Delta variant is so contagious that the vaccinated, even if they don’t get as sick as they otherwise would, can catch and potentially spread it. That’s resulted in about one in 51 people in Colorado being infectious – nearly as high as the infection rate during the pandemic’s early, unvaccinated days of 2020.

So basically, the vaccines are not effective at all at stopping the spread. It does seem, based on hospitalization numbers, that the vaccines help guard against a more severe case of COVID and reduces the likelyhood of hospitalization. But then, the reality is that the hospitalization rate for those with COVID is already very low for the unvaccinated as well except for those who are old or immune compromised.

The simplest reason that Colorado is seeing a leap in coronavirus cases now is that too few people have received at least one shot of the highly effective, extremely safe COVID-19 vaccine. The other part – why are case counts rising now? – is tougher to answer.

When I see items like this, I know this is a pure propaganda piece dressed up with whatever data can be provided to be used by even less knowledgeable people to sell a point of view. When something is objectively good, there is little reason to hype its sell. The reality is that its effectiveness is questionable if it is all but gone within 6 months and its safety is questionable when we see lots of reports of issues from heart and vascular problems, etc from those who have been vaccinated. If it really were that effective and that safe, many more people would be happy to get it.
 
When I see items like this, I know this is a pure propaganda piece dressed up with whatever data can be provided to be used by even less knowledgeable people to sell a point of view. When something is objectively good, there is little reason to hype its sell. The reality is that its effectiveness is questionable if it is all but gone within 6 months and its safety is questionable when we see lots of reports of issues from heart and vascular problems, etc from those who have been vaccinated. If it really were that effective and that safe, many more people would be happy to get it.

Gandalf, are you vaccinated? You do realize that The Precious was an etheric vaccine.
 
Looks like globally, there's a bit of an upturn. Mild so far. If you look at the big countries, there's mostly nothing, not a hint. Tiny uptick in USA. But then there's Russia. Booming there. They're out of sync with everybody else. Big surge in Germany. That is the only first world country I see.

Looks like anyway some form of shutdown is coming back in Europe. I'm not sure what happened to Russia. BBC says 32% vaccination rate there. Found an interesting (to me) BBC graphic.
_121167711_optimised-selected_second_dose_bars_rate_21oct-nc.png
 
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Looks like globally, there's a bit of an upturn. Mild so far. If you look at the big countries, there's mostly nothing, not a hint. Tiny uptick in USA. But then there's Russia. Booming there. They're out of sync with everybody else. Big surge in Germany. That is the only first world country I see.

Looks like anyway some form of shutdown is coming back in Europe. I'm not sure what happened to Russia. BBC says 32% vaccination rate there. Found an interesting (to me) BBC graphic.
_121167711_optimised-selected_second_dose_bars_rate_21oct-nc.png

I am trying to get a friend over from Germany to US and it ain't happening in any foreseeable future. He refuses what the Germans (in Eng) call "the jab". Moreover, a lockdown seems imminent to him and if he can get here, he could, potentially, not be able to return.

I cut all personal international travel way back when and I'm not going until I see clear signs of that peeps have come to their senses.
 
Gandalf, are you vaccinated? You do realize that The Precious was an etheric vaccine.

I am well vaccinated against the illogic and madness of crowds. I have this odd habit of reading things myself rather than gobbling down what is spoon-fed.

As to the One ring (and all the rings of power), it was less of a vaccine and more of a repository for the etheric where Sauron placed a part of his power. Indeed, what one needed was a vaccine against the ring's terrible call to power over all others. Fortunately, hobbits have rather strong natural immunity in this degree. Unfortunately, Wizards...not so much. Of note - there was a tale told by one of your modern authors (in a poor attempt to borrow from the historical legendarium of my time) that tried to express this concept of the ring as a "horcrux". Perhaps that would make the concept more familiar though no doubt less eloquent.
 
I am well vaccinated against the illogic and madness of crowds. I have this odd habit of reading things myself rather than gobbling down what is spoon-fed.

You may be Gandalf but, if I may, don't overreach your scientific capabilities. I can chart a course about Abstracts but the data...lol
 
Of note - there was a tale told by one of your modern authors (in a poor attempt to borrow from the historical legendarium of my time) that tried to express this concept of the ring as a "horcrux". Perhaps that would make the concept more familiar though no doubt less eloquent.

As a Harry Potter fan of significance, I did not know that.
 
You may be Gandalf but, if I may, don't overreach your scientific capabilities. I can chart a course about Abstracts but the data...lol

It is true, I am a wizard, not a scientist and do not claim to be - yet you might be surprised how many people these days claim to be wizards at interpreting "the science". Moreover, as a wizard I know that the data does not lie. It takes a data scientist (or a politician) to do that.
 
It is true, I am a wizard, not a scientist and do not claim to be - yet you might be surprised how many people these days claim to be wizards at interpreting "the science". Moreover, as a wizard I know that the data does not lie. It takes a data scientist (or a politician) to do that.

You do know the difference between skepticism and cynicism, yes?
 
You do know the difference between skepticism and cynicism, yes?

One's role is to challenge, the other to condemn.

One constantly examines the results to determine the best position, the other constantly examines the best spin on the results to justify their position.

To which camp do you think the results point to our current administration belonging?
 
One's role is to challenge, the other to condemn.

One constantly examines the results to determine the best position, the other constantly examines the best spin on the results to justify their position.

To which camp do you think the results point to our current administration belonging?

Sorry but my last post that was not at all political got splinched. Pass.
 
Sorry but my last post that was not at all political got splinched. Pass.

What is COVID doing would seem to be best in the realm of science and data as an objective (tho imperfectly measured) question
What to do about COVID is a question for the politicians and is subjective
Sadly, I fear that almost all camps now have now lost these distinctions.
 
SARS-CoV-2 Detection in Air Samples from Inside Heating, Ventilation, and Air Conditioning (HVAC) Systems- COVID Surveillance in Student Dorms
link: DEFINE_ME

Highlights

• HVAC air sampling was performed in a multi-floor student dorm to detect SARS-CoV-2.

• Three out of four air sampling methods with qRT-PCR analysis detected SARS-CoV-2.

• We detected SARS-CoV-2 in multiple air samples and correlated with clinical testing.

• HVAC air sampling provides surveillance for subclinical COVID infection detection.

• HVAC air sampling may be used to prevent and control disease spread.



Abstract

Background

The COVID-19 pandemic affected universities and institutions and caused campus shutdowns with a transition to online teaching models. To detect infections that might spread on campus, we pursued research towards detecting SARS-CoV-2 in air samples inside student dorms.

Methods

We sampled air in two large dormitories for 3.5 months and a separate isolation suite containing a student who had tested positive for COVID-19. We developed novel techniques employing four methods to collect air samples: Filter Cassettes, Button Sampler, BioSampler, and AerosolSense sampler combined with direct qRT-PCR SARS-CoV-2 analysis.

Results

For the two large dorms with the normal student population, we detected SARS-CoV-2 in 11 samples. When compared with student nasal swab qRT-PCR testing, we detected SARS-CoV-2 in air samples when a PCR positive COVID-19 student was living on the same floor of the sampling location with a detection rate of 75%. For the isolation dorm, we had a 100% SARS-CoV-2 detection rate with Aerosol Sense sampler.

Conclusion

Our data suggest air sampling may be an important SARS-CoV-2 surveillance technique, especially for buildings with congregant living settings (dorms, correctional facilities, barracks). Future building designs and public health policies should consider implementation of HVAC surveillance.
 
Looks like globally, there's a bit of an upturn. Mild so far. If you look at the big countries, there's mostly nothing, not a hint. Tiny uptick in USA. But then there's Russia. Booming there. They're out of sync with everybody else. Big surge in Germany. That is the only first world country I see.

Oops, I misread post. Actually the graph. Sorry. Edit!
 
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Covid causes the following:

  1. Type 1 diabetes with all its lifelong complications
  2. Myocarditis with nonischemic cardiomyopathy which may require short interim heart transplant in young patients
  3. Permanent pulmonary fibrosis which may require lifelong oxygen or lung transplantation. Greatly reduces life expectancy and quality
  4. blood clots which can cause all types of crazy stuff, including limb amputations
  5. Strokes with all of the associated debilitations
  6. Encephalitis/encephalopathy which can lead to someone being in a permanent vegetative state or now have a permanent dementia (even if young) and need to live in a nursing home or be fed through a tube for the rest of their life
  7. Brain shrinkage with an average IQ drop of 7
  8. Long-hauler syndrome
  9. All kinds of 2ndary infections
  10. Brain bleeding. Enough said there alone
  11. Covid toes. Look it up. It's real. They can even fall off.
  12. erectile dysfunction and sperm abnormalities
  13. Preterm labor in pregnant women
  14. Kidney damage and dialysis
And this isn't even including the long excruciating slog to rehabilitation from a basic uncomplicated Covid infection.

The current generation, especially the unvaxxed, is going to have a greatly decreased quality of life and life expectancy. It's already dropped by about 2 years since the pandemic started. The US is going to be a much sicker country with tremendous healthcare burden over the next 20-30 years, even moreso than it already is.
 
Spend some time in a country where 30% is vaccinated. See what anti-vaccination has wrought through Romania. (16 min doc about a Romanian covid unit, the last two minutes are brutal)

 

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