A few differences, including that we know that the Russians wanted him to win and were spending a ton to accomplish that; we know that the Russians infiltrated his campaign with persons tied to their intelligence apparatus; we know that the Russians worked with wikileaks to undermine his opponent.
Among many other points.
Not clear what I'm struggling about:
* Coronavirus is not Trump's fault
* Trump has in the past been anti-science because science tends to promote facts, which is just generally bad news for Trump, as a matter of principle;
* Trump struggles between the option of minimizing the virus in order to preserve a general "feel good" atmosphere in the country particular as to the economy, versus listening to those around him telling him this is not the time to do that and that he needs to focus attention and resources on a serious problem;
* Regardless of what route he takes on the above, Trump will portray himself at rallies as a victim of unfair criticism by the media, which his base loves as a constant theme;
* Trump slurpers will latch on to any criticism or any joke like the one we are discussing as proof positive that they must circle the wagons to defend against unfair criticism, particularly from the media. It keeps those checks rolling in.