Coronavirus (No politics)

mad4vols

Arsenal FC, Detroit Lions
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mad4vols

Arsenal FC, Detroit Lions
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Persistent Loss of Smell Due to COVID-19 Closely Connected to Long-Lasting Cognitive Problems

Loss of Smell from COVID-19, Cognitive Problems Linked | AAIC

Press release from this year's Alzheimer’s Association International Conference. Starts:

SAN DIEGO, JULY 31, 2022 — New insights into factors that may predict, increase or protect against the impact of COVID-19 and the pandemic on memory and thinking skills were revealed by multiple studies reported today at the Alzheimer’s Association International Conference® (AAIC®) 2022 in San Diego and virtually.​
Among the key findings reported at AAIC 2022:​
A group from Argentina found that persistent loss of the sense of smell may be a better predictor of long-term cognitive and functional impairment than severity of the initial COVID-19 disease.​
 

mad4vols

Arsenal FC, Detroit Lions
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Persistence of somatic symptoms after COVID-19 in the Netherlands: an observational cohort study

Summary​
Background​
Patients often report various symptoms after recovery from acute COVID-19. Previous studies on post-COVID-19 condition have not corrected for the prevalence and severity of these common symptoms before COVID-19 and in populations without SARS-CoV-2 infection. We aimed to analyse the nature, prevalence, and severity of long-term symptoms related to COVID-19, while correcting for symptoms present before SARS-CoV-2 infection and controlling for the symptom dynamics in the population without infection.​
Methods​
This study is based on data collected within Lifelines, a multidisciplinary, prospective, population-based, observational cohort study examining the health and health-related behaviours of people living in the north of the Netherlands. All Lifelines participants aged 18 years or older received invitations to digital COVID-19 questionnaires. Longitudinal dynamics of 23 somatic symptoms surrounding COVID-19 diagnoses (due to SARS-CoV-2 alpha [B.1.1.7] variant or previous variants) were assessed using 24 repeated measurements between March 31, 2020, and Aug 2, 2021. Participants with COVID-19 (a positive SARS-CoV-2 test or a physician's diagnosis of COVID-19) were matched by age, sex, and time to COVID-19-negative controls. We recorded symptom severity before and after COVID-19 in participants with COVID-19 and compared that with matched controls.​
Findings​
76 422 participants (mean age 53·7 years [SD 12·9], 46 329 [60·8%] were female) completed a total of 883 973 questionnaires. Of these, 4231 (5·5%) participants had COVID-19 and were matched to 8462 controls. Persistent symptoms in COVID-19-positive participants at 90–150 days after COVID-19 compared with before COVID-19 and compared with matched controls included chest pain, difficulties with breathing, pain when breathing, painful muscles, ageusia or anosmia, tingling extremities, lump in throat, feeling hot and cold alternately, heavy arms or legs, and general tiredness. In 12·7% of patients, these symptoms could be attributed to COVID-19, as 381 (21·4%) of 1782 COVID-19-positive participants versus 361 (8·7%) of 4130 COVID-19-negative controls had at least one of these core symptoms substantially increased to at least moderate severity at 90–150 days after COVID-19 diagnosis or matched timepoint. Interpretation​
To our knowledge, this is the first study to report the nature and prevalence of post-COVID-19 condition, while correcting for individual symptoms present before COVID-19 and the symptom dynamics in the population without SARS-CoV-2 infection during the pandemic. Further research that distinguishes potential mechanisms driving post-COVID-19-related symptomatology is required.​


 
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Sea Ray

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Persistent Loss of Smell Due to COVID-19 Closely Connected to Long-Lasting Cognitive Problems

Loss of Smell from COVID-19, Cognitive Problems Linked | AAIC

Press release from this year's Alzheimer’s Association International Conference. Starts:

SAN DIEGO, JULY 31, 2022 — New insights into factors that may predict, increase or protect against the impact of COVID-19 and the pandemic on memory and thinking skills were revealed by multiple studies reported today at the Alzheimer’s Association International Conference® (AAIC®) 2022 in San Diego and virtually.​
Among the key findings reported at AAIC 2022:​
A group from Argentina found that persistent loss of the sense of smell may be a better predictor of long-term cognitive and functional impairment than severity of the initial COVID-19 disease.​
How do they define "persistent" loss?
 

Gladiator1

Well-Known Member
Joined
Nov 24, 2020
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Persistent Loss of Smell Due to COVID-19 Closely Connected to Long-Lasting Cognitive Problems

Loss of Smell from COVID-19, Cognitive Problems Linked | AAIC

Press release from this year's Alzheimer’s Association International Conference. Starts:

SAN DIEGO, JULY 31, 2022 — New insights into factors that may predict, increase or protect against the impact of COVID-19 and the pandemic on memory and thinking skills were revealed by multiple studies reported today at the Alzheimer’s Association International Conference® (AAIC®) 2022 in San Diego and virtually.​
Among the key findings reported at AAIC 2022:​
A group from Argentina found that persistent loss of the sense of smell may be a better predictor of long-term cognitive and functional impairment than severity of the initial COVID-19 disease.​
Can I claim disability, asking for a friend.
 

ENGRVOL

Well-Known Member
Joined
Sep 16, 2009
Messages
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1,875
Persistence of somatic symptoms after COVID-19 in the Netherlands: an observational cohort study

Summary​
Background​
Patients often report various symptoms after recovery from acute COVID-19. Previous studies on post-COVID-19 condition have not corrected for the prevalence and severity of these common symptoms before COVID-19 and in populations without SARS-CoV-2 infection. We aimed to analyse the nature, prevalence, and severity of long-term symptoms related to COVID-19, while correcting for symptoms present before SARS-CoV-2 infection and controlling for the symptom dynamics in the population without infection.​
Methods​
This study is based on data collected within Lifelines, a multidisciplinary, prospective, population-based, observational cohort study examining the health and health-related behaviours of people living in the north of the Netherlands. All Lifelines participants aged 18 years or older received invitations to digital COVID-19 questionnaires. Longitudinal dynamics of 23 somatic symptoms surrounding COVID-19 diagnoses (due to SARS-CoV-2 alpha [B.1.1.7] variant or previous variants) were assessed using 24 repeated measurements between March 31, 2020, and Aug 2, 2021. Participants with COVID-19 (a positive SARS-CoV-2 test or a physician's diagnosis of COVID-19) were matched by age, sex, and time to COVID-19-negative controls. We recorded symptom severity before and after COVID-19 in participants with COVID-19 and compared that with matched controls.​
Findings​
76 422 participants (mean age 53·7 years [SD 12·9], 46 329 [60·8%] were female) completed a total of 883 973 questionnaires. Of these, 4231 (5·5%) participants had COVID-19 and were matched to 8462 controls. Persistent symptoms in COVID-19-positive participants at 90–150 days after COVID-19 compared with before COVID-19 and compared with matched controls included chest pain, difficulties with breathing, pain when breathing, painful muscles, ageusia or anosmia, tingling extremities, lump in throat, feeling hot and cold alternately, heavy arms or legs, and general tiredness. In 12·7% of patients, these symptoms could be attributed to COVID-19, as 381 (21·4%) of 1782 COVID-19-positive participants versus 361 (8·7%) of 4130 COVID-19-negative controls had at least one of these core symptoms substantially increased to at least moderate severity at 90–150 days after COVID-19 diagnosis or matched timepoint. Interpretation​
To our knowledge, this is the first study to report the nature and prevalence of post-COVID-19 condition, while correcting for individual symptoms present before COVID-19 and the symptom dynamics in the population without SARS-CoV-2 infection during the pandemic. Further research that distinguishes potential mechanisms driving post-COVID-19-related symptomatology is required.​


Long covid/postacute sequela of sarscov2 or whatever they call it seems to be the new fibromyalgia/chronic fatigue syndrome.
 

Jackcrevol

Don't be an Oxymoran!
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New Zealand allowed pharmacists to dispense COVID-19 antivirals and 'everyone realised it was a win'

Why some consider NZ's approach to COVID antivirals 'one of the best models around the world'

Makes a lot of sense. Why not leverage the broad distribution network of retail pharmacies. Plus trained pharmacists are well equipped to identify the need for antivirals. And it keeps the medical system from getting log jammed.
Honestly, this 'novel' approach is logical. Pharmacists are at front line if this deal anyway.
 

ENGRVOL

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kiddiedoc

Renaissance Man
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The back in here about natural immunity not helping was fun . Lol
Ms. Jean-Pierre:

"Look, we knew this was going to happen. As Dr. Jha said, you know, when he was — when he joined me at the briefing — in the briefing room not too long ago, he said this is — this is — you know, everyone was — at some point, everyone is going to get COVID."
 

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