I don't like to throw around absolutes, but Louisville will never be elite. I honestly believe that they're going to make incredible strides in the coming years, but "elite" is a tough thing to become. Notre Dame? Alabama? OSU/Michigan? Even the real Tennessee that's primed to return to prominence in the coming seasons... Louisville is highly unlikely to vault itself into that realm.
A national title this year, though? Only an absolute idiot would deny the possibility of them playing for it all if they go undefeated.
P.S. I think they really do win it all, but that's my colors showing and a lot of hoping to get that far. My practical self sees Louisville finishing #3, behind Ohio State and eventual champ Stanford.