WriterVol
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Not sure why it takes a few months to start the trials, ie review, sample production, etc, but they need to get their ass in gear and start asap. I am curious to know how long it will take for actual production of billions of vaccines after the review is completed.
There is a ton of literature on the subject, but mostly it involves making sure the vaccine is effective at preventing the targeted disease and that it doesn't do more harm than good. Efficacy and safety.
Some vaccine trials have resulted in heightened risk of infection from other pathogens for example. Sometimes it might do unexpected things to the immune system in some populations but not others. There are a ton of things that can go wrong. Trials try to make sure those problems aren't present before they release it to millions or billions of people.